Invention Application
US20020177564A1 METHOD FOR MODULATING EXPRESSION OF EXOGENOUS GENES IN MAMMALIAN SYSTEMS, AND PRODUCTS RELATED THERETO 失效
用于调节MAMMALIAN系统中外源基因表达的方法及其相关产品

  • Patent Title: METHOD FOR MODULATING EXPRESSION OF EXOGENOUS GENES IN MAMMALIAN SYSTEMS, AND PRODUCTS RELATED THERETO
  • Patent Title (中): 用于调节MAMMALIAN系统中外源基因表达的方法及其相关产品
  • Application No.: US09042488
    Application Date: 1998-03-16
  • Publication No.: US20020177564A1
    Publication Date: 2002-11-28
  • Inventor: RONALD M. EVANSDAVID NOENRIQUE SAEZ
  • Main IPC: A61K048/00
  • IPC: A61K048/00 C12Q001/68 C07H021/04
METHOD FOR MODULATING EXPRESSION OF EXOGENOUS GENES IN MAMMALIAN SYSTEMS, AND PRODUCTS RELATED THERETO
Abstract:
In accordance with the present invention, there are provided various methods for modulating the expression of an exogenous gene in a mammalian subject employing modified ecdysone receptors. Also provided are modified ecdysone receptors, as well as homomeric and heterodimeric receptors containing same, nucleic acids encoding invention modified ecdysone receptors, modified ecdysone response elements, gene transfer vectors, recombinant cells, and transgenic animals containing nucleic acids encoding invention modified ecdysone receptor.
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