Invention Application
US20030015190A1 Delivery of compounds for the treatment of migraine through an inhalation route 失效
输送化合物用于通过吸入途径治疗偏头痛

  • Patent Title: Delivery of compounds for the treatment of migraine through an inhalation route
  • Patent Title (中): 输送化合物用于通过吸入途径治疗偏头痛
  • Application No.: US10154594
    Application Date: 2002-05-23
  • Publication No.: US20030015190A1
    Publication Date: 2003-01-23
  • Inventor: Joshua D. RabinowitzAlejandro C. Zaffaroni
  • Main IPC: A61M011/00
  • IPC: A61M011/00 A61M016/10
Delivery of compounds for the treatment of migraine through an inhalation route
Abstract:
The present invention relates to the delivery of a migraine headache drug through an inhalation route. Specifically, it relates to aerosols containing a migraine headache drug that are used in inhalation therapy. In a composition aspect of the present invention, the aerosol comprises particles comprising at least 5 percent by weight of a migraine headache drug. In a method aspect of the present invention, a migraine headache drug is delivered to a mammal through an inhalation route. The method comprises: a) heating a composition, wherein the composition comprises at least 5 percent by weight of a migraine headache drug, to form a vapor; and, b) allowing the vapor to cool, thereby forming a condensation aerosol comprising particles, which is inhaled by the mammal. In a kit aspect of the present invention, a kit for delivering a migraine headache drug through an inhalation route to a mammal is provided which comprises: a) a composition comprising at least 5 percent by weight of a migraine headache drug; and, b) a device that forms a migraine headache drug containing aerosol from the composition, for inhalation by the mammal.
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