发明申请
- 专利标题： Family of immunoregulators designated leukocyte immunoglobulin-like receptors (LIR)
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申请号： US10139683申请日： 2002-05-02
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公开(公告)号： US20030060614A1公开(公告)日： 2003-03-27
- 发明人: David J. Cosman , Dirk M. Anderson , Luis G. Borges
- 申请人： Immunex Corporation
- 申请人地址： null
- 专利权人： Immunex Corporation
- 当前专利权人： Immunex Corporation
- 当前专利权人地址： null
- 主分类号： C07K016/16
- IPC分类号： C07K016/16 ; C07H021/04 ; C12P021/02 ; C12N005/06
摘要：
A new family of immunoreceptor molecules of the immunoglobulin superfamily, (LIR) polypeptides is described. Disclosed are sequences encoding LIR family members and their deduced amino acid sequences, polypeptides encoded by DNA that hybridizes to defined nucleotide sequences, processes for producing polypeptides of the LIR family, and specific antibodies directed against LIR polypeptides. LIR family members can be used to treat autoimmune diseases and disease states associated with suppressed immune function.
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