发明申请
US20030077250A1 Method for selectively transducing pathologic mammalian cells using a tumor suppressor gene
审中-公开
使用肿瘤抑制基因选择性转导病理性哺乳动物细胞的方法
- 专利标题： Method for selectively transducing pathologic mammalian cells using a tumor suppressor gene
- 专利标题（中）： 使用肿瘤抑制基因选择性转导病理性哺乳动物细胞的方法
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申请号： US10076691申请日： 2002-02-14
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公开(公告)号： US20030077250A1公开(公告)日： 2003-04-24
- 发明人: H. Michael Shepard , Nancy Kan
- 申请人： Canji, Inc.
- 申请人地址： US CA San Diego
- 专利权人： Canji, Inc.
- 当前专利权人： Canji, Inc.
- 当前专利权人地址： US CA San Diego
- 主分类号： A61K048/00
- IPC分类号： A61K048/00 ; C12N015/867
摘要：
A method for transducing a pathologic hyperproliferative mammalian cell is provided by this invention. This method requires contacting the cell with a suitable retroviral vector containing a nucleic acid encoding a gene product having a tumor suppressive function. Also provided by this invention is a method for treating a pathology in a subject caused by the absence of, or the presence of a pathologically mutated tumor suppressor gene.
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