- 专利标题： Substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity
-
申请号： US10154571申请日： 2002-05-23
-
公开(公告)号： US20030119833A1公开(公告)日： 2003-06-26
- 发明人: James A. Sikorski , Richard C. Durley , Deborah A. Mischke , Emily J. Reinhard , Yvette M. Fobian , Michael B. Tollefson , Lijuan Wang , Margaret L. Grapperhaus , Brian S. Hickory , Mark A. Massa , Monica B. Norton , William F. Vernier , Barry L. Parnas , Michele A. Promo , Ashton T. Hamme , Dale P. Spangler , Melvin L. Rueppel
- 申请人： G.D. Searle & Co.
- 申请人地址： IL Chicago
- 专利权人： G.D. Searle & Co.
- 当前专利权人： G.D. Searle & Co.
- 当前专利权人地址： IL Chicago
- 主分类号： C07D43/02
- IPC分类号： C07D43/02 ; A61K031/53 ; A61K031/506 ; A61K031/501 ; A61K031/497 ; A61K031/444 ; A61K031/137
摘要：
The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating atherosclerosis and other coronary artery diseases.
公开/授权文献
信息查询
