An apparatus and methods for the adjustment of the position of a die in a printing press are disclosed. The apparatus and methods provide for the adjustment of a die frame within a chase. The chase defines a horizontal and a vertical axis. The die frame is slidably secured in a chase to permit movement and adjustment of the die frame in the horizontal and the vertical axis. The die frame may be slidably mounted to one or more vertical guides and one or more horizontal guides to facilitate movement and adjustment in the horizontal and vertical axis.