发明申请
US20030186382A1 Novel antiangiogenic peptide agents and their therapeutic and diagnostic use
审中-公开
新型抗血管生成肽剂及其治疗和诊断用途
- 专利标题: Novel antiangiogenic peptide agents and their therapeutic and diagnostic use
- 专利标题(中): 新型抗血管生成肽剂及其治疗和诊断用途
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申请号: US09819094申请日: 2001-03-27
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公开(公告)号: US20030186382A1公开(公告)日: 2003-10-02
- 发明人: Richard I. Weiner , Joseph A. Martial , Ingrid Struman , Robert Taylor , Frauke Bentzien
- 主分类号: A61K038/27
- IPC分类号: A61K038/27 ; C12P021/02 ; C07H021/04 ; C12N005/06 ; C07K014/61
摘要:
The current invention concerns novel antiangiogenic peptides which correspond to about 10 to about 150 consecutive amino acids of N-terminal sequences of human growth hormone, human placental lactogen, human growth hormone variant hGH-V, and prolactin, and their use in inhibiting angiogenesis and in the diagnosis of diseases of human pregnancy involving abnormalities of placental vascularization.