发明申请
US20030232973A1 High-affinity, low-molecular-mass displacers for ion-exchange chromatography
失效
用于离子交换层析的高亲和力，低分子量的置换剂
- 专利标题： High-affinity, low-molecular-mass displacers for ion-exchange chromatography
- 专利标题（中）： 用于离子交换层析的高亲和力，低分子量的置换剂
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申请号： US10377080申请日： 2003-02-28
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公开(公告)号： US20030232973A1公开(公告)日： 2003-12-18
- 发明人: Steven M. Cramer , James A. Moore , Sun Kyu Park , Nihal Tugcu
- 申请人： Rensselaer Polytechnic Institute
- 申请人地址： US NY Troy
- 专利权人： Rensselaer Polytechnic Institute
- 当前专利权人： Rensselaer Polytechnic Institute
- 当前专利权人地址： US NY Troy
- 主分类号： C07H021/04
- IPC分类号： C07H021/04 ; C08B037/00 ; C07K001/18
摘要：
A method for separating one or more components of a biomolecule mixture by means of an ion exchange chromatographic system operated in the displacement mode includes sequentially perfusing the system with a first solution including the biomolecule mixture, and a second solution including a displacer having a structure selected from formula I and formula II: 1
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