Invention Application
- Patent Title: Method of inducing apoptosis by reducing the level of thiamin
- Patent Title (中): 通过降低硫胺素水平诱导凋亡的方法
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Application No.: US10342119Application Date: 2003-01-13
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Publication No.: US20040013658A1Publication Date: 2004-01-22
- Inventor: Chandler Fulton , Elaine Y. Lai
- Applicant: Brandeis University
- Applicant Address: null
- Assignee: Brandeis University
- Current Assignee: Brandeis University
- Current Assignee Address: null
- Main IPC: A61K038/43
- IPC: A61K038/43 ; A61K048/00
Abstract:
The disclosure describes methods for inducing apoptosis of a selected group of vertebrate cells in vivo by reducing the level of thiamin in the cells. Included are methods for inducing apoptosis of cancer cells. Also described are compounds and compositions for use in methods of thiamin depletion and treating diseases such as cancer, and methods for identifying thiamin-depleting agents and for preparing pharmaceutical compositions.
Public/Granted literature
- US07803531B2 Method of inducing apoptosis by reducing the level of thiamin Public/Granted day:2010-09-28
Information query
