A machine tool for machining large-area workpieces. A column can be moved along one coordinate axis over a long bed. A machining unit, movable at the movable column along at least two other coordinate axes, has a pivotable working spindle. At least one approximately plate-like work carrier can be pivoted from a horizontal set-up position into a vertical machining position. A tripod configuration of the machining unit has a central support pipe and three telescopic legs spaced about 120null with respect to one another. The movable column has, in a central recess, a universal bearing supporting the central support pipe. In each of two lower and one upper recesses a universal bearing for the telescopic legs is provided. A retainer supporting the pivotable working spindle is positioned next to the work area on one end of the central support pipe and is rotatable about an axis of the central support pipe.