发明申请
- 专利标题: Gene therapy for hemophilia a
- 专利标题(中): 血友病基因治疗
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申请号: US10480887申请日: 2004-05-18
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公开(公告)号: US20040192599A1公开(公告)日: 2004-09-30
- 发明人: Andre C Schuh , Edward M Conway
- 主分类号: A61K038/37
- IPC分类号: A61K038/37 ; A61K048/00 ; C07H021/04
摘要:
Nucleic acid constructs comprising procoagulant gene sequences under the control of a megakaryocyte-specific promoter are provided. The sequences preferably also comprise a secretory granule sorting domain Also provided are vectors comprising the sequences and methods of gene therapy comprising the use of the various constructs.
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