发明申请
US20040214318A1 Method for enhancing RNA or protein production using non-native 5' untranslated sequences in recombinant viral nucleic acids
审中-公开
在重组病毒核酸中使用非天然5'非翻译序列增强RNA或蛋白质产生的方法
- 专利标题: Method for enhancing RNA or protein production using non-native 5' untranslated sequences in recombinant viral nucleic acids
- 专利标题(中): 在重组病毒核酸中使用非天然5'非翻译序列增强RNA或蛋白质产生的方法
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申请号: US10858775申请日: 2004-06-01
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公开(公告)号: US20040214318A1公开(公告)日: 2004-10-28
- 发明人: Sean Chapman , William O. Dawson , Jonothan Donson , Monto H. Kumagai , Dennis J. Lewandowski , John A. Lindbo , Gregory P. Pogue , Shailaja Shivprasad
- 主分类号: C07H021/04
- IPC分类号: C07H021/04 ; C12N015/09 ; C12N015/63 ; C12N005/04 ; C12N015/87 ; C12N015/00 ; C12N015/70 ; C12N015/85
摘要:
The present invention provides a method for enhancing the production of RNAs or proteins in a plant host using either non-native 5null untranslated sequences or artificial leader sequences. Preferably, commercially useful proteins, polypeptides, or fusion products thereof are produced, such as, enzymes, antibodies, hormones, pharmaceuticals, vaccines, pigments, anti-microbial polypeptides, and the like. The non-native 5null untranslated enhancers may also be effective in many different types of transcription or translation systems, such as bacterial and animal systems.
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