发明申请
US20040224394A1 Recombinant Streptomyces hygroscopicus host cells that produce 17-desmethylrapamycin
审中-公开
产生17-去甲基雷帕霉素的重组链霉菌吸湿链菌宿主细胞
- 专利标题： Recombinant Streptomyces hygroscopicus host cells that produce 17-desmethylrapamycin
- 专利标题（中）： 产生17-去甲基雷帕霉素的重组链霉菌吸湿链菌宿主细胞
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申请号： US10690949申请日： 2003-10-21
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公开(公告)号： US20040224394A1公开(公告)日： 2004-11-11
- 发明人: Leonard Katz , Lu Liu , Loleta M. Chung
- 主分类号： C12P017/18
- IPC分类号： C12P017/18 ; A61K031/4745 ; C12N001/21 ; C07D487/14
摘要：
Recombinant host cells that produce rapamycin analogues are constructed by deleting or modifying rapamycin biosynthetic gene cluster genes and are useful in the production of compounds used as antifungals, anticancers, immunosuppressants, and neurotrophins.
公开/授权文献
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