发明申请
US20040235135A1 Manipulation of negative stranded RNA viruses by rearrangement of their genes and uses thereof
审中-公开
通过重组其基因来控制负链RNA病毒及其用途
- 专利标题： Manipulation of negative stranded RNA viruses by rearrangement of their genes and uses thereof
- 专利标题（中）： 通过重组其基因来控制负链RNA病毒及其用途
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申请号： US10872706申请日： 2004-06-21
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公开(公告)号： US20040235135A1公开(公告)日： 2004-11-25
- 发明人: Gail W. Wertz , Andrew L. Ball
- 申请人： Research Development Foundation
- 申请人地址： null
- 专利权人： Research Development Foundation
- 当前专利权人： Research Development Foundation
- 当前专利权人地址： null
- 主分类号： C12N007/00
- IPC分类号： C12N007/00 ; C12N015/86
摘要：
The present invention provides a method of increasing expression of a promoter distal gene in a virus of the order Mononegavirales, and a recombinant virus constructed by such method. Also provided is a method of attenuating a virus of the order Mononegavirales, and of constructing an attenuated virus useful for a vaccine.
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