发明申请
US20040235924A1 Imidazolyl derivatives as corticotropin releasing factor inhibitors
有权
咪唑衍生物作为促肾上腺皮质激素释放因子抑制剂
- 专利标题： Imidazolyl derivatives as corticotropin releasing factor inhibitors
- 专利标题（中）： 咪唑衍生物作为促肾上腺皮质激素释放因子抑制剂
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申请号： US10772027申请日： 2004-02-04
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公开(公告)号： US20040235924A1公开(公告)日： 2004-11-25
- 发明人: Xiaojun Han , Gene M. Dubowchik , John E. Macor
- 主分类号： A61K031/4172
- IPC分类号： A61K031/4172 ; C07D233/28
摘要：
The present invention relates to novel heterocyclic antagonists of Formula (I) and pharmaceutical compositions comprising said antagonists of the corticotropin releasing factor receptor (nullCRF receptornull) 1 useful for the treatment of depression, anxiety, affective disorders, feeding disorders, post-traumatic stress disorder, headache, drug addiction, inflammatory disorders, drug or alcohol withdrawal symptoms and other conditions the treatment of which can be effected by the antagonism of the CRF-1 receptor.