发明申请
US20040253674A1 Family of immunoregulators designated leukocyte immunoglobulin-like receptors (LIR)
审中-公开
免疫调节剂家族称为白细胞免疫球蛋白样受体（LIR）
- 专利标题： Family of immunoregulators designated leukocyte immunoglobulin-like receptors (LIR)
- 专利标题（中）： 免疫调节剂家族称为白细胞免疫球蛋白样受体（LIR）
-
申请号： US10745447申请日： 2003-12-22
-
公开(公告)号： US20040253674A1公开(公告)日： 2004-12-16
- 发明人: David J. Cosman
- 申请人： Immunex Corporation
- 申请人地址： null
- 专利权人： Immunex Corporation
- 当前专利权人： Immunex Corporation
- 当前专利权人地址： null
- 优先权： TW91205234 20020418
- 主分类号： C07K014/47
- IPC分类号： C07K014/47 ; C07H021/04
摘要：
A new family of immunoreceptor molecules of the immunoglobulin superfamily, (LIR) polypeptides is described. Disclosed are sequences encoding LIR family members and their deduced amino acid sequences, polypeptides encoded by DNA that hybridize to oligonucleotide probes having defined sequences, processes for producing polypeptides of the LIR family, and antagonistic antibodies to LIR family members. LIR family members can be used to treat autoimmune diseases and disease states associated with suppressed immune function.
信息查询
