发明申请
- 专利标题： Histone deacetylase inhibitors
- 专利标题（中）： 组蛋白脱乙酰酶抑制剂
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申请号： US10803575申请日： 2004-03-17
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公开(公告)号： US20040254220A1公开(公告)日： 2004-12-16
- 发明人: Jerome C. Bressi , Jason W. Brown , Sheldon X. Cao , Anthony R. Gangloff , Andrew J. Jennings , Jeffrey A. Stafford , Phong H. Vu , Xiao-Yi Xiao
- 申请人： Syrrx, Inc.
- 申请人地址： null
- 专利权人： Syrrx, Inc.
- 当前专利权人： Syrrx, Inc.
- 当前专利权人地址： null
- 主分类号： A61K031/454
- IPC分类号： A61K031/454 ; C07D43/04
摘要：
Compounds that may be used to inhibit histone deacetylase having the formula Z-Q-L-M or Z-L-M wherein M is a substituent capable of complexing with a deacetylase catalytic site and/or a metal ion; L is a substituent providing between 0-10 atoms separation between the M substituent and the remainder of the compound; and Z and Q are as defined herein.
公开/授权文献
- US07381825B2 Histone deacetylase inhibitors 公开/授权日：2008-06-03