发明申请
US20050004163A1 3-(diarylmethylene)-8-azabicyclo[3.2.1]octane derivatives
审中-公开
3-(二芳基亚甲基)-8-氮杂双环[3.2.1]辛烷衍生物
- 专利标题: 3-(diarylmethylene)-8-azabicyclo[3.2.1]octane derivatives
- 专利标题(中): 3-(二芳基亚甲基)-8-氮杂双环[3.2.1]辛烷衍生物
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申请号: US10767712申请日: 2004-01-29
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公开(公告)号: US20050004163A1公开(公告)日: 2005-01-06
- 发明人: Steven Coats , John Carson , Lou Neilson , Philip Pitis , Mark Schulz
- 申请人: Steven Coats , John Carson , Lou Neilson , Philip Pitis , Mark Schulz
- 主分类号: A61K31/439
- IPC分类号: A61K31/439 ; C07D451/02 ; A61K31/46
摘要:
This invention is directed to 3-(diarylmethylene)-8-azabicyclo[3.2.1]octane derivatives useful as δ-opioid or μ-opioid receptor modulators. Depending on their agonist or antagonist effect, the compounds are useful analgesics, immunosuppressants, antiinflammatory agents, agents for the treatment of neurological and psychiatric conditions, medicaments for drug and alcohol abuse, agents for treating gastritis and diarrhea, cardiovascular agents and agents for the treatment of respiratory diseases.
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