发明申请
US20050004187A1 Thiazolyl-indole derivatives, their manufacture and use as pharmaceutical agents
失效
噻唑基 - 吲哚衍生物，其制造和用作药剂
- 专利标题： Thiazolyl-indole derivatives, their manufacture and use as pharmaceutical agents
- 专利标题（中）： 噻唑基 - 吲哚衍生物，其制造和用作药剂
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申请号： US10878473申请日： 2004-06-28
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公开(公告)号： US20050004187A1公开(公告)日： 2005-01-06
- 发明人: Jean Ackermann , Johannes Aebi , Alfred Binggeli , Uwe Grether , Georges Hirth , Bernd Kuhn , Hans-Peter Maerki , Markus Meyer , Peter Mohr , Matthew Wright
- 申请人： Jean Ackermann , Johannes Aebi , Alfred Binggeli , Uwe Grether , Georges Hirth , Bernd Kuhn , Hans-Peter Maerki , Markus Meyer , Peter Mohr , Matthew Wright
- 优先权： EP03014476.0 20030702; EP04100157.9 20040120
- 主分类号： A61P3/04
- IPC分类号： A61P3/04 ; A61P3/10 ; C07D417/12 ; A61K31/426 ; C07D417/02
摘要：
This invention relates to compounds of the formula wherein one of R6, R7 or R8 is and all enantiomers and pharmaceutically acceptable salts and/or esters thereof as well as pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPARδ and/or PPARα agonists.
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