发明申请
US20050004213A1 5-[phenyl-tetrahydronaphthalene-2-yl dihydronaphthalen-2-yl and heteroaryl-cyclopropyl]-pentadienoic acid derivatives having serum glucose reducing activity
失效
具有血清葡萄糖还原活性的5- [苯基 - 四氢萘-2-基二氢萘-2-基和杂芳基 - 环丙基] - 戊二烯酸衍生物
![5-[phenyl-tetrahydronaphthalene-2-yl dihydronaphthalen-2-yl and heteroaryl-cyclopropyl]-pentadienoic acid derivatives having serum glucose reducing activity](/docs/US/2005-01-06/US20050004213A1/abs.jpg.600x600.jpg)
- 专利标题： 5-[phenyl-tetrahydronaphthalene-2-yl dihydronaphthalen-2-yl and heteroaryl-cyclopropyl]-pentadienoic acid derivatives having serum glucose reducing activity
- 专利标题（中）： 具有血清葡萄糖还原活性的5- [苯基 - 四氢萘-2-基二氢萘-2-基和杂芳基 - 环丙基] - 戊二烯酸衍生物
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申请号： US10606603申请日： 2003-06-26
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公开(公告)号： US20050004213A1公开(公告)日： 2005-01-06
- 发明人: Santosh Sinha , Kwok Tsang , Smita Bhat , Roshantha Chandraratna
- 申请人： Santosh Sinha , Kwok Tsang , Smita Bhat , Roshantha Chandraratna
- 主分类号： A61P3/10
- IPC分类号： A61P3/10 ; C07C59/72 ; C07C69/74 ; A61K31/215
![5-[phenyl-tetrahydronaphthalene-2-yl dihydronaphthalen-2-yl and heteroaryl-cyclopropyl]-pentadienoic acid derivatives having serum glucose reducing activity](/abs-image/US/2005/01/06/US20050004213A1/abs.jpg.150x150.jpg)
摘要：
Compounds of the formula where the variables have the meaning defined in the specification are capable of reducing serum glucose levels in diabetic mammals without the undesirable side effects of reducing serum thyroxine levels and transiently increasing triglyceride levels.
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