发明申请
US20050009154A1 Biocatalytic preparation of 1-cyano-cyclohexaneacetic acid
审中-公开
1-氰基 - 环己烷乙酸的生物催化制备
- 专利标题： Biocatalytic preparation of 1-cyano-cyclohexaneacetic acid
- 专利标题（中）： 1-氰基 - 环己烷乙酸的生物催化制备
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申请号： US10869518申请日： 2004-06-16
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公开(公告)号： US20050009154A1公开(公告)日： 2005-01-13
- 发明人: John Wong , Michael Burns
- 申请人： John Wong , Michael Burns
- 专利权人： Pfizer Inc
- 当前专利权人： Pfizer Inc
- 主分类号： C12P7/40
- IPC分类号： C12P7/40 ; C12P13/00
摘要：
The present invention is directed to novel biocatalytic processes for the conversion of aliphatic ∝, ω-dinitriles into the corresponding ω-nitrilecarboxylic acid. More particularly, the present invention provides a method for the conversion of 1-cyanocyclohexaneacetonitrile to 1-cyanocyclohexaneacetic acid using an enzyme catalyst with nitrilase activity. 1-cyanocyclohexaneacetic acid is a useful intermediate in the synthesis of gabapentin.
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