发明申请
- 专利标题: Predicting hepatotoxicity using cell based assays
- 专利标题(中): 使用基于细胞的测定预测肝毒性
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申请号: US10623486申请日: 2003-07-18
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公开(公告)号: US20050014216A1公开(公告)日: 2005-01-20
- 发明人: Larry Mattheakis , Jay Trautman , Gregg Solar , Jinhong Fan , Eugeni Vaisberg , Cynthia Adams , Aibing Rao
- 申请人: Larry Mattheakis , Jay Trautman , Gregg Solar , Jinhong Fan , Eugeni Vaisberg , Cynthia Adams , Aibing Rao
- 专利权人: Cytokinetics, Inc.
- 当前专利权人: Cytokinetics, Inc.
- 主分类号: G01N1/30
- IPC分类号: G01N1/30 ; G01N33/50 ; G06T7/00 ; G01N33/48
摘要:
Cell based assays are used to assess the hepatotoxicity of a stimulus. Imaging technologies are used to analyze the effects of a stimulus on hepatocytes. Image analysis may characterize the stimulus on the basis of whether it is hepatotoxic, and if so what type of pathology is exhibited; e.g., apoptosis, necrosis, cholestasis, and/or steatosis.
公开/授权文献
- US07235353B2 Predicting hepatotoxicity using cell based assays 公开/授权日:2007-06-26
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