利索-全球专利检索

  1. 登录
  2. 注册
发明申请
US20050020534A1 Method for treating diseases using HSP90-inhibiting agents in combination with antimetabolites 审中-公开
使用HSP90抑制剂与抗代谢药联合治疗疾病的方法

Method for treating diseases using HSP90-inhibiting agents in combination with antimetabolites
摘要：
The present invention provides a method for treating cancer. The method involves the administration of an HSP90 inhibitor and an antimetabolite, where the combined administration provides a synergistic effect. In one aspect of the invention, a method of treating cancer is provided where a subject is treated with a dose of an HSP90 inhibitor in one step and a dose of an antimetabolite in another step. In another aspect of the invention, a method of treating cancer is provided where a subject is first treated with a dose of an HSP90 inhibitor and subsequently treated with a dose of an antimetabolite. In another aspect of the invention, a method of treating cancer is provided where a subject is first treated with a dose of an antimetabolite and subsequently treated with a dose of an HSP90 inhibitor.
摘要（中）：

本发明提供一种治疗癌症的方法。 该方法包括施用HSP90抑制剂和抗代谢物，其中组合给药提供协同效应。 在本发明的一个方面，提供了一种治疗癌症的方法，其中在一个步骤中用一种HSP90抑制剂的剂量治疗受试者，另一步中使用抗代谢药剂量。 在本发明的另一方面，提供了一种治疗癌症的方法，其中首先用一种剂量的HSP90抑制剂治疗受试者，并随后用一种抗代谢药物剂量治疗。 在本发明的另一方面，提供了一种治疗癌症的方法，其中首先用抗体代谢物剂量治疗受试者，随后用剂量的HSP90抑制剂治疗。

信息查询
Global Dossier
Espacenet
0/0