发明申请
US20050027008A1 Cancer remedy comprising anthranilic acid derivatives as active ingredient 审中-公开
包括邻氨基苯甲酸衍生物作为活性成分的癌症治疗

Cancer remedy comprising anthranilic acid derivatives as active ingredient
摘要:
A cancer remedy comprising a compound represented by the following formula as an active ingredient: wherein, X represents a group represented by either of the following formulae: wherein, R1 and R2 represent each a hydrogen atom, a hydroxy group, a trihalomethyl group, a C1-C12 alkoxy group or alkylthio group, a (substituted) C7-C11 aralkyloxy group or a (substituted) C3-C10 alkenyloxy group; R4 and R5 represent each a hydrogen atom, a halogen atom, a C1-C4 alkyl group or a C1-C4 alkoxy group; A represents —O—, —S—, —S(═O)—, —S(═O)2—, —CH2—, —OCH2—, —SCH2, —C(═O)— or —CH(OR6)—; Y represents a hydrogen atom, a halogen atom, a nitro group, a nitrile group, an amino group, —COOR7, —NHCOR8 or —NHSO2R9−; E represents —C(═O)—, —CR10R11C(═O)—, —CH2CH2C(═O)— or —CH═CHC(═O)—; G represents a hydrogen atom, a hydroxy group, —SO2NH2, —COOR3, —CN or a tetrazol-5-yl group; and Z represents a hydrogen atom, a halogen atom, a nitro group or a methyl group.
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