发明申请
- 专利标题： Serotonin reuptake inhibitor formulations
- 专利标题（中）： 5-羟色胺再摄取抑制剂制剂
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申请号： US10746324申请日： 2003-12-23
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公开(公告)号： US20050027011A1公开(公告)日： 2005-02-03
- 发明人: Chih-Ming Chen , Boyong Li , Janice Cacace
- 申请人： Chih-Ming Chen , Boyong Li , Janice Cacace
- 申请人地址： US FL Davie
- 专利权人： Andrx Corporation
- 当前专利权人： Andrx Corporation
- 当前专利权人地址： US FL Davie
- 主分类号： A61K9/14
- IPC分类号： A61K9/14 ; A61K9/16 ; A61K9/20 ; A61K9/28 ; A61K31/135 ; A61K31/4525 ; A61K31/137
摘要：
A process for preparing amorphous paroxetine hydrochloride or sertraline hydrochloride is provided, which comprises preparing a solution in which paroxetine hydrochloride or sertraline hydrochloride and a water-soluble polymer are dissolved in a co-solvent of a volatile organic solvent and water. Said solution is dried to obtain a composition comprising amorphous paroxetine hydrochloride or sertraline hydrochloride and the water-soluble matrix.
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