发明申请
- 专利标题： LTA4 hydrolase inhibitors
- 专利标题（中）： LTA4水解酶抑制剂
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申请号： US10900384申请日： 2004-10-19
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公开(公告)号： US20050027013A1公开(公告)日： 2005-02-03
- 发明人: Denis Danvy , Thierry Monteil , Jean-Christophe Plaquevent , Pierre Duhamel , Lucette Duhamel , Nadine Noel , Claude Gros , Olivier Chamard , Jean-Charles Schwartz , Jeanne-Marie Lecomte , Serge Piettre
- 申请人： Denis Danvy , Thierry Monteil , Jean-Christophe Plaquevent , Pierre Duhamel , Lucette Duhamel , Nadine Noel , Claude Gros , Olivier Chamard , Jean-Charles Schwartz , Jeanne-Marie Lecomte , Serge Piettre
- 优先权： FR9904271 19990406
- 主分类号： A61K31/662
- IPC分类号： A61K31/662 ; A61K31/085 ; A61K31/09 ; A61K31/198 ; A61K31/215 ; A61K31/223 ; A61K31/225 ; A61K31/27 ; A61K31/695 ; A61P1/16 ; A61P17/06 ; A61P19/02 ; A61P29/00 ; A61P43/00 ; C07C45/30 ; C07C47/277 ; C07C229/08 ; C07C229/22 ; C07C251/02 ; C07F9/38 ; C07F9/40 ; A61K31/137
摘要：
The invention relates to compounds which constitute a class of medicaments which have an anti-inflammatory activity and which act by inhibiting leukotriene A4 (LTA4), and enzyme which is responsible for the biosynthesis of leukotriene LTB4, a major proinflammatory mediator. The invention also relates to therapeutic anti-inflammatory, applications of these compounds as well as for methods of preparing these compounds.
公开/授权文献
- US07094773B2 LTA4 hydrolase inhibitors 公开/授权日：2006-08-22
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