Invention Application
- Patent Title: Bis-transition-metal-chelate probes
- Patent Title (中): 双过渡金属螯合探针
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Application No.: US10946786Application Date: 2004-09-21
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Publication No.: US20050031545A1Publication Date: 2005-02-10
- Inventor: Richard Ebright , Yon Ebright
- Applicant: Richard Ebright , Yon Ebright
- Assignee: Rutgers, The State University of New Jersey
- Current Assignee: Rutgers, The State University of New Jersey
- Main IPC: C07D209/14
- IPC: C07D209/14 ; C12Q1/68 ; G01N33/533 ; A61K51/00

Abstract:
A molecule for labeling a target material is provided including two transition-metal chelates and a detectable group. The molecule has the general structural formula (I): wherein: (a) Y and Y′ are each a transition metal, (b) R1 and R1′ are each independently CH(COO−), CH(COOH), or absent; (c) R2 and R2′ are linkers each having a length of from about 3.0 to about 20 Å; and (d) X is a detectable group. The linkers may be linear or branched, may contain aromatic moieties, and may optionally be further substituted. Methods of using the molecules of the invention as probes in detecting and analyzing target materials as well as kits including the molecule of the invention are also provided.
Public/Granted literature
- US07371745B2 Bis-transition-metal-chelate probes Public/Granted day:2008-05-13
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