发明申请
US20050037341A1 Method of monitoring a biological system by labeling with an apo metal binding protein
有权
通过用载脂蛋白结合蛋白标记来监测生物系统的方法
- 专利标题： Method of monitoring a biological system by labeling with an apo metal binding protein
- 专利标题（中）： 通过用载脂蛋白结合蛋白标记来监测生物系统的方法
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申请号： US10935838申请日： 2004-09-08
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公开(公告)号： US20050037341A1公开(公告)日： 2005-02-17
- 发明人: Inge Dierynck , Christiaan Hubert Roelant , Rudi Wilfried Pauwels , Koenraad Lodewijk Van Acker , Jan Octaaf De Kerpel
- 申请人： Inge Dierynck , Christiaan Hubert Roelant , Rudi Wilfried Pauwels , Koenraad Lodewijk Van Acker , Jan Octaaf De Kerpel
- 专利权人： Tibotec, N.V.
- 当前专利权人： Tibotec, N.V.
- 主分类号： G01N33/50
- IPC分类号： G01N33/50 ; G01N33/58 ; C12Q1/70 ; G01N33/554 ; G01N33/569
摘要：
The present invention is directed to reporter molecules and tags that may be used to monitor a target substance in a biological system. More particularly, the present invention relates to the use of an apo metal binding protein as a reporter molecule or tag. An apo metal binding protein may be bound to a protein or tissue or introduced into a cell. The invention also relates to methods of utilizing the apo metal binding protein for detecting a cell expressing a protein of interest, localizing a protein in a cell, and designing a therapeutic agent for treating a disease or infection.
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