A method is described for generating a reference current for sense amplifiers connected to cells of a memory matrix comprising the steps of generating a first reference current analog signal through a reference cell, performing an analog-to-digital conversion of the first analog signal into a reference current digital signal, sending the digital signal on a connection line to the sense amplifiers, and performing a digital-to-analog conversion of the digital signal into a second reference current analog signal to be applied as reference current to the sense amplifiers.