发明申请
US20050043535A1 4-(Piperidyl-and pyrrolidyl-alkyl-ureido)-quinolines as urotensin II receptor antagonists
失效
4-（哌啶基和吡咯烷基 - 烷基 - 脲基） - 喹啉作为尿素转运蛋白II受体拮抗剂
- 专利标题： 4-(Piperidyl-and pyrrolidyl-alkyl-ureido)-quinolines as urotensin II receptor antagonists
- 专利标题（中）： 4-（哌啶基和吡咯烷基 - 烷基 - 脲基） - 喹啉作为尿素转运蛋白II受体拮抗剂
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申请号： US10501054申请日： 2002-12-02
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公开(公告)号： US20050043535A1公开(公告)日： 2005-02-24
- 发明人: Hamed Aissaoui , Christoph Binkert , Martine Clozel , Boris Mathys , Claus Mueller , Oliver Nayler , Michael Scherz , Jorg Velker , Thomas Weller
- 申请人： Hamed Aissaoui , Christoph Binkert , Martine Clozel , Boris Mathys , Claus Mueller , Oliver Nayler , Michael Scherz , Jorg Velker , Thomas Weller
- 优先权： WOPCT/EP01/14195 20011204
- 国际申请： PCT/EP02/13577 WO 20021202
- 主分类号： A61K31/4709
- IPC分类号： A61K31/4709 ; A61P9/02 ; C07D20060101 ; C07D401/12 ; C07D401/14 ; C07D471/04 ; C07D471/02 ; C07D41/02
摘要：
The invention relates to novel 1-pyridin-4-yl urea derivatives and related compounds and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as neurohormonal antagonists.
公开/授权文献
- US07375227B2 Quinoline derivatives 公开/授权日：2008-05-20