发明申请
- 专利标题： TGF-beta activation and use
- 专利标题（中）： TGF-β激活和使用
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申请号： US10987919申请日： 2004-11-12
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公开(公告)号： US20050065089A1公开(公告)日： 2005-03-24
- 发明人: Bret Ferree
- 申请人： Bret Ferree
- 主分类号： A61K38/18
- IPC分类号： A61K38/18 ; A61K38/20
摘要：
Proteases are added to Platelet Rich Plasma (PRP) along with calcium and thrombin to activate latent TGF-β. The proteases include plasmin, calpin, MMP-9, thrombospondin, transglutaminase, the mannose 6-phosphate receptor (M6PR), furin, substilisin-like endoproteases, and integrins. Dermatopontin can also be added to the PRP to enhance its biologic activity.
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