发明申请
US20050070544A1 1,2,5,10-tetrahydropyridazino{4,5-b}quinoline-1,10-diones and their use for the treatment of pain
审中-公开
1,2,5,10-四氢哒嗪（4,5-b）喹啉-1,10-二酮及其用于治疗疼痛的用途
- 专利标题： 1,2,5,10-tetrahydropyridazino{4,5-b}quinoline-1,10-diones and their use for the treatment of pain
- 专利标题（中）： 1,2,5,10-四氢哒嗪（4,5-b）喹啉-1,10-二酮及其用于治疗疼痛的用途
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申请号： US10381914申请日： 2001-09-28
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公开(公告)号： US20050070544A1公开(公告)日： 2005-03-31
- 发明人: Megan Murphy , Wenhua Xiao , Dean Brown , Rebecca Urbanek , Frances MClaren , Edward Vacek , Thomas Bare , Carey Horchler , Christine Barlaam , Gary Steelman , Vernon Alford
- 申请人： Megan Murphy , Wenhua Xiao , Dean Brown , Rebecca Urbanek , Frances MClaren , Edward Vacek , Thomas Bare , Carey Horchler , Christine Barlaam , Gary Steelman , Vernon Alford
- 专利权人： AstraZeneca AB
- 当前专利权人： AstraZeneca AB
- 国际申请： PCT/SE01/02124 WO 20010928
- 主分类号： A61K31/5025
- IPC分类号： A61K31/5025 ; A61K31/503 ; A61P25/04 ; C07D471/04 ; C07D487/02
摘要：
Compounds are disclosed according to structural diagram (1), wherein R1, A, D and E are as defined in the specification. Also disclosed are methods for the treatment of pain and pharmaceutical compositions comprising a pain-ameliorating effective amount of a compound in accord with structural diagram (1).