发明申请
US20050074409A1 Use of perfluoroalkyl-containing metal complexes as contrast media in MR-imaging for visualization of plaque, tumors and necroses
审中-公开
在MR成像中使用含全氟烷基的金属络合物作为造影剂，用于斑块，肿瘤和坏死物的可视化
- 专利标题： Use of perfluoroalkyl-containing metal complexes as contrast media in MR-imaging for visualization of plaque, tumors and necroses
- 专利标题（中）： 在MR成像中使用含全氟烷基的金属络合物作为造影剂，用于斑块，肿瘤和坏死物的可视化
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申请号： US10857877申请日： 2004-06-02
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公开(公告)号： US20050074409A1公开(公告)日： 2005-04-07
- 发明人: Johannes Platzek , Peter Mareski , Ulrich Niedballa , Bernd Raduechel , Hanns-Joachim Weinmann , Bernd Misselwitz
- 申请人： Johannes Platzek , Peter Mareski , Ulrich Niedballa , Bernd Raduechel , Hanns-Joachim Weinmann , Bernd Misselwitz
- 优先权： DE10040380.8 20000811
- 主分类号： A61K49/08
- IPC分类号： A61K49/08 ; A61K49/10 ; A61K49/00
摘要：
The invention relates to the use of perfluoroalkyl-containing metal complexes that have a critical micelle formation concentration 1 nm and a proton relaxivity in plasma (R1)>10 I/mmol.s) as contrast media in MR imaging for visualization of plaque, lymph nodes, infarcted and necrotic tissue and for independent visualization of necrotic tissue and tumor tissue.
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