发明申请
- 专利标题: Substituted benzofuran-2-carboxamides derivatives
- 专利标题(中): 取代的苯并呋喃-2-甲酰胺衍生物
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申请号: US10471584申请日: 2002-02-27
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公开(公告)号: US20050075269A1公开(公告)日: 2005-04-07
- 发明人: Dieter Dorsch , Henning Böttcher , Christoph van Amsterdam , Wilfried Rautenberg , Gerd Bartoszyk
- 申请人: Dieter Dorsch , Henning Böttcher , Christoph van Amsterdam , Wilfried Rautenberg , Gerd Bartoszyk
- 优先权: DE10112151.2 20010314
- 国际申请: PCT/EP02/02093 WO 20020227
- 主分类号: A61K31/496
- IPC分类号: A61K31/496 ; A61K31/5377 ; A61P1/14 ; A61P3/04 ; A61P5/24 ; A61P9/10 ; A61P9/12 ; A61P15/00 ; A61P15/10 ; A61P25/02 ; A61P25/18 ; A61P25/20 ; A61P25/22 ; A61P25/24 ; A61P25/28 ; A61P29/00 ; A61P43/00 ; C07D405/12 ; C07D405/14 ; C07D407/14 ; C07D409/14 ; A61K31/00
摘要:
Compounds of the formula (I), in which D, R1, R2 and n are defined in Claim 1, are potent 5-HT1A agonists and 5-HT reuptake inhibitors and are suitable for the treatment of depression, anxiety states, panic attacks, obsessive-compulsive disorders, psychiatric illnesses, cerebral infarction, cerebral ischaemia, tension states, side-effects in the treatment of high blood pressure, for the prophylaxis and therapy of cerebral illnesses, acromegaly, hypogonadism, secondary amenorrhoea, premenstrual syndrome, undesired puerperal lactation, pain, sleep disorders, narcolepsy, bipolar illnesses, mania, dementia, addiction illnesses, sexual dysfunction, eating disorders, obesity or fibromyalgia.
公开/授权文献
- US07244846B2 Substituted benzofuran-2-carboxamides derivatives 公开/授权日:2007-07-17
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