- 专利标题： Functionalized heterocycles as modulators of chemokine receptor function and methods of use therefor
-
申请号： US10983929申请日： 2004-11-08
-
公开(公告)号： US20050075348A1公开(公告)日： 2005-04-07
- 发明人: Geraldine Harriman , Kenneth Carson , Daniel Flynn , Michael Solomon , Yuntao Song , Bharat Trivedi , Bruce Roth , Christine Kolz , Ly Pham , Kuai-lin Sun
- 申请人： Geraldine Harriman , Kenneth Carson , Daniel Flynn , Michael Solomon , Yuntao Song , Bharat Trivedi , Bruce Roth , Christine Kolz , Ly Pham , Kuai-lin Sun
- 申请人地址： US MA Cambridge
- 专利权人： Millennium Pharmaceuticals, Inc.
- 当前专利权人： Millennium Pharmaceuticals, Inc.
- 当前专利权人地址： US MA Cambridge
- 主分类号： A61P31/18
- IPC分类号： A61P31/18 ; C07D209/42 ; C07D235/26 ; C07D401/04 ; C07D401/06 ; C07D401/12 ; C07D401/14 ; C07D403/12 ; C07D405/12 ; C07D487/04 ; C07D491/04 ; C07D491/08 ; A61K31/519 ; A61K31/52 ; A61K31/53
摘要：
Disclosed are novel compounds having the formula or a physiologically acceptable salt, amide, ester or prodrug thereof. The compounds can be used to modulate (antagonize, agonize) chemokine receptor function. Also disclosed is a method for treating a patient having an inflammatory disease and/or viral infection comprising administering an effective amount of a compound of Formula I. In particular embodiments, the invention is a method for treating a patient infected with HIV.
信息查询
