发明申请
US20050084868A1 Generation of stabilized proteins by combinatorial consensus mutagenesis
审中-公开
通过组合共有突变产生稳定的蛋白质
- 专利标题： Generation of stabilized proteins by combinatorial consensus mutagenesis
- 专利标题（中）： 通过组合共有突变产生稳定的蛋白质
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申请号： US10688255申请日： 2003-10-16
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公开(公告)号： US20050084868A1公开(公告)日： 2005-04-21
- 发明人: Wolfgang Aehle , Sandra Ramer , Volker Schellenberger
- 申请人： Wolfgang Aehle , Sandra Ramer , Volker Schellenberger
- 主分类号： C07K14/705
- IPC分类号： C07K14/705 ; C12N9/86 ; C12N15/10 ; C12Q1/68 ; C12P19/34
摘要：
The present invention provides methods and compositions for the production of stabilized proteins. In particular, the present invention provides methods and compositions for the generation of combinatorial libraries of consensus mutations and screening for improved protein variants.