发明申请
US20050085441A1 Use of soluble monovalent oligosaccharides as inhibitors of HIV-1 fusion and replication
审中-公开
使用可溶性一价低聚糖作为HIV-1融合和复制的抑制剂
- 专利标题： Use of soluble monovalent oligosaccharides as inhibitors of HIV-1 fusion and replication
- 专利标题（中）： 使用可溶性一价低聚糖作为HIV-1融合和复制的抑制剂
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申请号： US10797730申请日： 2004-03-10
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公开(公告)号： US20050085441A1公开(公告)日： 2005-04-21
- 发明人: James Leach , Stacey Borowicz , Pedro Prieto , Balbino Alarcon , Ricardo Rueda , Enrique Vazquez
- 申请人： James Leach , Stacey Borowicz , Pedro Prieto , Balbino Alarcon , Ricardo Rueda , Enrique Vazquez
- 主分类号： A61K31/715
- IPC分类号： A61K31/715
摘要：
The subject invention relates to monovalent oligosaccharides and their use, for example, in the treatment and prevention of mammalian disease caused by HIV-1 virus infections. In particular, the oligosaccharides globotriose and lactose may be used alone or in combination to competitively inhibit the formation of the viral fusion complex that occurs upon infection.
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