发明申请
US20050085625A1 Chimeric Galpha 15 variants and their use in the analysis and discovery of modulators of G-protein coupled receptors
审中-公开
嵌合Galpha 15变体及其在分析和发现G蛋白偶联受体调节剂中的应用
- 专利标题: Chimeric Galpha 15 variants and their use in the analysis and discovery of modulators of G-protein coupled receptors
- 专利标题(中): 嵌合Galpha 15变体及其在分析和发现G蛋白偶联受体调节剂中的应用
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申请号: US10319821申请日: 2002-12-16
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公开(公告)号: US20050085625A1公开(公告)日: 2005-04-21
- 发明人: Xiaodong Li , Hong Xu , Lena Staszewski , Jon Adler
- 申请人: Xiaodong Li , Hong Xu , Lena Staszewski , Jon Adler
- 专利权人: Senomyx, Inc.
- 当前专利权人: Senomyx, Inc.
- 主分类号: C07K14/47
- IPC分类号: C07K14/47 ; C07H21/04 ; C07K14/705
摘要:
The invention provides a series of chimeric Gα15 protein variants that couple to certain GPCRs more efficiently than the native Gα15 protein. These chimeric Gα15 protein variants can be used to discover and analyze modulators of GPCRs (especially those that mediate taste perception).
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