发明申请
- 专利标题： Human receptor proteins; related reagents and methods
- 专利标题（中）： 人受体蛋白; 相关试剂和方法
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申请号： US10975909申请日： 2004-10-28
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公开(公告)号： US20050112659A1公开(公告)日： 2005-05-26
- 发明人: Gerard Hardiman , Fernando Rock , J. Bazan , Robert Kastelein , Stephen Ho , Yong-Jun Liu
- 申请人： Gerard Hardiman , Fernando Rock , J. Bazan , Robert Kastelein , Stephen Ho , Yong-Jun Liu
- 专利权人： Schering Corporation
- 当前专利权人： Schering Corporation
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K14/705 ; C12Q1/68 ; C07H21/04 ; C07K16/28
摘要：
Nucleic acids encoding mammalian Toll-like receptors (TLRs) have been identified in human cells. Recombinantly produced TLRs are used in the preparation of antibodies that are capable of binding to the TLRs. The antibodies are advantageously used in the prevention and treatment of septic shock, inflammatory conditions, and viral infections.
公开/授权文献
- US07271248B2 Human receptor proteins; related reagents and methods 公开/授权日：2007-09-18
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