发明申请
- 专利标题： Bicyclic pyrazolone cytokine inhibitors
- 专利标题（中）： 双环吡唑啉酮细胞因子抑制剂
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申请号： US10983114申请日： 2004-11-05
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公开(公告)号： US20050113392A1公开(公告)日： 2005-05-26
- 发明人: Michael Clark , Steven Laughlin , Adam Golebiowski , Todd Brugel , Mark Sabat
- 申请人： Michael Clark , Steven Laughlin , Adam Golebiowski , Todd Brugel , Mark Sabat
- 申请人地址： US OH Cincinnati
- 专利权人： The Procter & Gamble Company
- 当前专利权人： The Procter & Gamble Company
- 当前专利权人地址： US OH Cincinnati
- 主分类号： A61K31/506
- IPC分类号： A61K31/506 ; C07D487/04
摘要：
The present invention relates to 6,7-dihydro-5H-pyrazolo[1,2a]pyrazol-1-ones which inhibit the extracellular release of inflammatory cytokines, said cytokines responsible for one or more human or higher mammalian disease states. The present invention further relates to compositions comprising said 6,7-dihydro-5H-pyrazolo[1,2a]pyrazol-1-ones and methods for preventing, abating, or otherwise controlling enzymes which are understood to be the active components responsible for the herein described disease states.
公开/授权文献
- US07482356B2 Bicyclic pyrazolone cytokine inhibitors 公开/授权日：2009-01-27
信息查询
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