发明申请
- 专利标题: Modulators of angiogenesis and tumorigenesis
- 专利标题(中): 血管发生和肿瘤发生的调节剂
-
申请号: US10696909申请日: 2003-10-29
-
公开(公告)号: US20050118604A1公开(公告)日: 2005-06-02
- 发明人: James Lorens , Robert Atchison , Annabelle Friera , Sacha Holland
- 申请人: James Lorens , Robert Atchison , Annabelle Friera , Sacha Holland
- 申请人地址: US CA South San Francisco
- 专利权人: Rigel Pharmaceuticals, Incorporated
- 当前专利权人: Rigel Pharmaceuticals, Incorporated
- 当前专利权人地址: US CA South San Francisco
- 主分类号: C07K14/47
- IPC分类号: C07K14/47 ; C12N9/00 ; G01N33/50 ; C12Q1/68 ; C07H21/04 ; G01N33/574
摘要:
The present invention relates to regulation of angiogenesis and tumorigenesis. The invention further relates to methods for identifying and using agents, including small organic molecules, antibodies, peptides, cyclic peptides, nucleic acids, antisense nucleic acids, RNAi, and ribozymes, that modulate angiogenesis via modulation of endothelial cell haptotaxis; as well as to the use of expression profiles and compositions in diagnosis and therapy of angiogenesis and cancer.
公开/授权文献
- US08574827B2 Modulators of angiogenesis and tumorigenesis 公开/授权日:2013-11-05
信息查询