发明申请
- 专利标题： Non-endogenous, constitutively activated human serotonin receptors and small molecule modulators thereof
- 专利标题（中）： 非内源性，组成型激活的人血清素受体及其小分子调节剂
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申请号： US10980560申请日： 2004-11-02
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公开(公告)号： US20050119182A1公开(公告)日： 2005-06-02
- 发明人: Dominic Behan , Derek Chalmers , Chen Liaw , Joseph Russo , William Thomsen
- 申请人： Dominic Behan , Derek Chalmers , Chen Liaw , Joseph Russo , William Thomsen
- 申请人地址： US CA San Diego
- 专利权人： Arena Pharmaceuticals, Inc.
- 当前专利权人： Arena Pharmaceuticals, Inc.
- 当前专利权人地址： US CA San Diego
- 主分类号： C07D231/12
- IPC分类号： C07D231/12 ; C07D231/16 ; C07D409/12 ; C07K14/705 ; C07K14/72 ; G01N33/566 ; A61K38/17 ; C07H21/04
摘要：
Disclosed herein are non-endogenous, constitutively activated forms of the human 5-HT2A and human 5-HT2C receptors and uses of such receptors to screen candidate compounds. Further disclosed herein are candidate compounds identified by the screening method which act at the 5HT2A receptors. Yet further disclosed is a new class of compounds which act at the 5HT2A receptors.
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