发明申请
US20050124043A1 Chemokine-like factors (CKLFs) with chemotactic and hematopoietic stimulating activities
失效
趋化因子样因子(CKLFs)具有趋化性和造血刺激活性
- 专利标题: Chemokine-like factors (CKLFs) with chemotactic and hematopoietic stimulating activities
- 专利标题(中): 趋化因子样因子(CKLFs)具有趋化性和造血刺激活性
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申请号: US10859414申请日: 2004-06-02
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公开(公告)号: US20050124043A1公开(公告)日: 2005-06-09
- 发明人: Dalong Ma , Wenling Han , Yingmei Zhang , Quansheng Song , Chunhui Di , Jiaqiang Huang , Jian Tang , Guanghui Chen
- 申请人: Dalong Ma , Wenling Han , Yingmei Zhang , Quansheng Song , Chunhui Di , Jiaqiang Huang , Jian Tang , Guanghui Chen
- 申请人地址: CN Beijing CN Beijing
- 专利权人: Bejing Medical University,Bejing Medical University United Biological Engineering Company
- 当前专利权人: Bejing Medical University,Bejing Medical University United Biological Engineering Company
- 当前专利权人地址: CN Beijing CN Beijing
- 优先权: CN99107284.7 19990514
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; C07K14/52 ; C12N15/19 ; C07H21/04 ; C12P21/02
摘要:
The present invention provides chemokine-like factor (CKLF) polypeptides with chemotactic and hematopoietic stimulating activities and polynucleotides encoding such polypeptides. Additionally, a method for producing such CKLF polypeptides by recombinant techniques is provided. Also provided are the antibodies and antagonists against such polypeptides. The present invention further disclose a drug compound comprising a therapeutically effective amount of such CKLF polypeptides as well as pharmaceutically acceptable excipients and carriers. Also disclosed are the uses of such CKLF polypeptides and polynucleotides in diagnostics or therapeutics to treat immunodeficiency, hematopoietic diseases and primary tumors.
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