- 专利标题: Spirocyclic quinuclidinic ether derivatives
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申请号: US11013193申请日: 2004-12-15
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公开(公告)号: US20050137219A1公开(公告)日: 2005-06-23
- 发明人: Jianguo Ji , Tao Li
- 申请人: Jianguo Ji , Tao Li
- 主分类号: A61K31/4747
- IPC分类号: A61K31/4747 ; C07D491/14 ; C07D491/20
摘要:
Compounds of formula (I) wherein n1 is 0, 1, or 2; n2 is 0, 1, or 2; X is a bond, O, S, or NR1; and Ar1 is a 5-membered aromatic ring, 6-membered aromatic ring, or a fused bicycloheterocycle. The compounds are useful in treating conditions or disorders prevented by or ameliorated by α7 nAChR ligands. Also disclosed are pharmaceutical compositions having compounds of formula (I) and methods for using such compounds and compositions.
公开/授权文献
- US07045530B2 Spirocyclic quinuclidinic ether derivatives 公开/授权日:2006-05-16
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