发明申请
- 专利标题: Growth hormone secretagogues
- 专利标题(中): 生长激素促分泌素
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申请号: US10932675申请日: 2004-09-02
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公开(公告)号: US20050143318A1公开(公告)日: 2005-06-30
- 发明人: Jeffrey Dodge , Charles Lugar
- 申请人: Jeffrey Dodge , Charles Lugar
- 主分类号: A61K38/04
- IPC分类号: A61K38/04 ; C07D401/06 ; C07K5/02 ; C07K5/04 ; C07K5/06 ; C07D43/02
摘要:
What is disclosed are growth hormone secretagogues, and their uses, of formula (I) wherein R1 is C6H5CH2OCH2—, C6H5(CH2)3— or indol-3-ylmethyl; Y is pyrrolidin-1-yl, 4-C1-C6 alkylpiperidin-1-yl or NR2R2; R2 are each independently a C1 to C6 alkyl; R3 is 2-napthyl or phenyl para-substituted by W; W is H, F, CF3, C1-C6 alkoxy or phenyl; and R4 is H or CH3, or a pharmaceutically acceptable salt or solvate thereof.
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