发明申请
US20050143453A1 Selective preventing and therapeutic agents for progressive lesion after organic damage
审中-公开
有机损伤后进行性病变的选择性预防和治疗剂
- 专利标题： Selective preventing and therapeutic agents for progressive lesion after organic damage
- 专利标题（中）： 有机损伤后进行性病变的选择性预防和治疗剂
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申请号： US11045394申请日： 2005-01-31
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公开(公告)号： US20050143453A1公开(公告)日： 2005-06-30
- 发明人: Michio Ishibashi , Alain Wagner , Charles Mioskowski , Catherine Sylvain
- 申请人： Michio Ishibashi , Alain Wagner , Charles Mioskowski , Catherine Sylvain
- 优先权： JP88990/2000 20000328; JP289458/2000 20000922
- 主分类号： A61K31/341
- IPC分类号： A61K31/341 ; A61K31/343 ; A61K31/365 ; A61P1/18 ; A61P13/12 ; A61P37/06 ; A61P43/00 ; C07D307/33 ; C07D307/68 ; C07D305/12 ; C07D307/62
摘要：
An object of the present invention is to provide a pharmaceutical agents for preventing and/or treating the progressive lesion after the organic damage without inhibiting organic function or regeneration function thereof, by selectively suppressing the induction of cytotoxic effector macrophages which are induced into the damaged organs in response to chemokines and cytokines which are expressed depending on the type of damaged organic tissues.
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