发明申请
- 专利标题: Fused pentacyclic polyethers
- 专利标题(中): 稠合五环聚醚
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申请号: US10945471申请日: 2004-09-20
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公开(公告)号: US20050148539A1公开(公告)日: 2005-07-07
- 发明人: Daniel G. Baden , William Abraham , Andrea Bourdelais
- 申请人: Daniel G. Baden , William Abraham , Andrea Bourdelais
- 申请人地址: US NC Wilmington
- 专利权人: University of North Carolina
- 当前专利权人: University of North Carolina
- 当前专利权人地址: US NC Wilmington
- 主分类号: A61K31/35
- IPC分类号: A61K31/35 ; A61K31/353 ; A61K31/42 ; A61K31/7072 ; C07D493/04 ; C07D493/14 ; C07D493/22 ; C07H19/04
摘要:
Disclosed are polycyclic polyether compounds of formula I and pharmaceutical compositions comprising such compounds. wherein R, OR1, and R2 are as defined herein. Also disclosed are methods of regulating mucus clearance in a cell, and methods of treating decreased mucus clearance or mucociliary dysfunction.
公开/授权文献
- US07202271B2 Fused pentacyclic polyethers 公开/授权日:2007-04-10
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