发明申请
US20050148633A1 Method for modulating calcium ion-release-activated calcium ion channels
审中-公开
钙离子释放活化钙离子通道调节方法
- 专利标题： Method for modulating calcium ion-release-activated calcium ion channels
- 专利标题（中）： 钙离子释放活化钙离子通道调节方法
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申请号： US10897682申请日： 2004-07-22
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公开(公告)号： US20050148633A1公开(公告)日： 2005-07-07
- 发明人: Yu Xie , Mats Holmqvist , Jerome Mahiou , Mitsunori Ono , Lijun Sun , Shoujun Chen , Shijie Zhang , Jun Jiang , Dinesh Chimmanamada , Andrea Fleig , Chih-Yi Yu
- 申请人： Yu Xie , Mats Holmqvist , Jerome Mahiou , Mitsunori Ono , Lijun Sun , Shoujun Chen , Shijie Zhang , Jun Jiang , Dinesh Chimmanamada , Andrea Fleig , Chih-Yi Yu
- 主分类号： A61K31/35
- IPC分类号： A61K31/35 ; A61K31/381 ; A61K31/40 ; A61K31/41 ; A61K31/415 ; A61K31/4196 ; A61K31/42 ; A61K31/4439 ; A61K31/444 ; A61K31/535 ; A61K31/724 ; A61P20060101 ; A61P27/00 ; C07D20060101
摘要：
The invention relates to a method for modulating Ca2+-release-activated Ca2+ channels (CRAC) in a cell by administering to the cell a compound of formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, or prodrug thereof wherein X, Y, A, Z, L and n are defined herein.
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