发明申请
- 专利标题: Pharmaceutical composition which improves in vivo gene transfer
- 专利标题(中): 改善体内基因转移的药物组合物
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申请号: US10502973申请日: 2003-02-07
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公开(公告)号: US20050152870A1公开(公告)日: 2005-07-14
- 发明人: Bruno Pitard
- 申请人: Bruno Pitard
- 申请人地址: FR Paris 75013
- 专利权人: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
- 当前专利权人: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
- 当前专利权人地址: FR Paris 75013
- 优先权: FR02/01584 20020208
- 国际申请: PCT/FR03/00407 WO 20030207
- 主分类号: A61K47/04
- IPC分类号: A61K47/04 ; A61K31/7088 ; A61K31/77 ; A61K31/785 ; A61K38/16 ; A61K38/46 ; A61K47/34 ; A61K48/00 ; A61P21/00 ; A61P43/00
摘要:
The invention relates to a pharmaceutical composition which combines a tetrafunctional copolymer with a nucleic acid, said copolymer having formula I (namely a poloxamine), and preferably taking the form of one of the cationic mineral or organic salts thereof. The inventive composition can be used to improve in vivo gene transfer.
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