发明申请
US20050153965A1 Substituted polycyclic aryl and heteroaryl pyridines useful for selective inhibition of the coagulation cascade
审中-公开
用于选择性抑制凝血级联的取代的多环芳基和杂芳基吡啶
- 专利标题： Substituted polycyclic aryl and heteroaryl pyridines useful for selective inhibition of the coagulation cascade
- 专利标题（中）： 用于选择性抑制凝血级联的取代的多环芳基和杂芳基吡啶
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申请号： US11004437申请日： 2004-12-03
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公开(公告)号： US20050153965A1公开(公告)日： 2005-07-14
- 发明人: Michael South , Brenda Case , Danny Garland , Michael Hayes , Horng-Chih Huang , Wei Huang , Darin Jones , William Neumann , John Parlow , David Reitz , Melvin Rueppel , Ronald Webber
- 申请人： Michael South , Brenda Case , Danny Garland , Michael Hayes , Horng-Chih Huang , Wei Huang , Darin Jones , William Neumann , John Parlow , David Reitz , Melvin Rueppel , Ronald Webber
- 申请人地址： US MO St. Louis
- 专利权人： Pharmacia Corporation
- 当前专利权人： Pharmacia Corporation
- 当前专利权人地址： US MO St. Louis
- 主分类号： A61K31/44
- IPC分类号： A61K31/44 ; A61K31/4418 ; A61K31/4436 ; A61K31/4439 ; A61K45/00 ; A61P7/02 ; A61P9/10 ; A61P11/00 ; A61P35/00 ; A61P43/00 ; C07D213/74 ; C07D213/89 ; C07D401/10 ; C07D409/04 ; C07D43/02 ; A61K31/444 ; A61K31/497 ; A61K31/501 ; A61K31/506 ; A61K31/53 ; C07D41/02
摘要：
The present invention relates to compounds, and prodrugs thereof, composition and methods useful for preventing and treating thrombotic conditions in mammals. The compounds of the present invention, and prodrugs thereof, selectively inhibit certain proteases of the coagulation cascade.
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